From Yuma, AZ exit Interstate 8 at Winterhaven Road and head north. Travel for a quarter mile, and make a sharp right to Picacho Road. Drive on Picacho Road for 19 miles to the campground.
Overwhelming displays of wild wetlands in the desert. A delightful place. Explore the back canyons for other wonders. Remote, and worth the effort. I would not try w/o 4x4 (saw 2 flats & 1 broken axle & broken shock along roadside). This place can bite back. But my 4x4 Tundra truck had no issues in 4H, and I used 4L in the back canyon. Been back twice, going again.
There is some great off roading in this area with excellent views. High clearance 4x4 is needed on some of the trails. Just know your vehicle capabilities and keep your ego in check and turn around if needed.